When women experience bedwetting in the middle of the night, it is likely that there is a chronic urinary tract infection, which causes bladder irritation symptoms, or it may be due to primary overactive bladder disorder. It is best to have further examination, including urinary routine, urine culture, and urodynamic examination, which can basically clarify the diagnosis. If it is caused by chronic urinary tract infection, sensitive antibiotics can be selected according to the specific type of pathogenic microorganism, such as furantoin tablets and sulfadiazine tablets, and continued oral treatment for a period of time, and the bedwetting will not be repeated after the inflammation has healed. If it is clear through examination that it is caused by overactive bladder disorder, usually some oral medications to stabilize bladder function, such as tolterodine tartrate tablets, solifenacin succinate tablets, mirabellum extended-release tablets, etc., are taken symptomatically before bedtime, after which problems such as bedwetting at night will not occur. In addition to medication, patients should maintain good habits, don’t be sedentary and don’t hold urine, eat less spicy and stimulating things, and don’t drink coffee, strong tea and other beverages with stimulating properties as much as possible.