Hepatitis B patients with medication must be three taboos a persistent: one, avoid drug abuse: drugs are metabolized by the liver, taking more drugs is extremely detrimental to liver health, so if there is a need for medication, must be under the guidance of a professional doctor, follow medical advice standardized medication, in order to effectively reduce the damage to the liver. Second, avoid blind medication: there is no clinical treatment for “chronic hepatitis B” of the special drugs, blindly applied not only to the treatment is not beneficial, but also can aggravate liver damage, is not conducive to the recovery of the disease, serious cases can also lead to deterioration of the disease, complications of cirrhosis, or liver cancer. Third, avoid arbitrarily modify the dosage and time of medication: the dosage of drugs is appropriate for the weight and varies from person to person, the size of the dosage, the time of medication before and after meals, the method of medication should be strictly in accordance with medical advice to implement, especially hepatitis B antiviral drugs, do not arbitrarily modify, in order to prevent increased metabolic burden on the liver, inducing viral mutations, affecting the treatment and recovery process of the disease. The main items are liver function, liver ultrasound, and HBV-DNA testing, in order to observe the treatment effect of the disease and to detect the occurrence of hepatitis B virus mutation and drug resistance in time to take effective treatment remedial measures early.