Sleeping at night with a scratchy throat and cough may be caused by allergic laryngitis, reflux pharyngitis, cough variant asthma, etc., which can be treated through general therapy, medication, etc. 1. Allergic pharyngolaryngitis: generally due to contact with allergens caused by the itchy throat, cough, etc., the patient needs to stay away from allergens, you can use loratadine tablets and other anti-allergy drugs to relieve. 2. Reflux laryngitis: stomach contents reflux to the throat, stimulate the mucous membrane of the throat, cause throat itching, foreign body sensation, cough and so on. It is recommended to prohibit eating sweet, sour, spicy and stimulating foods, and apply acid-suppressing drugs, such as omeprazole, etc., gastrointestinal dynamics of drugs, such as mosapride hydrochloride and other medications. 3. Cough variant asthma: cough is mostly irritating dry cough, mainly at night. Treatment to avoid contact with allergens, can be applied to β2 agonists, such as salbutamol, formoterol, etc.; glucocorticoid sprays, such as fluticasone propionate and other drugs; leukotriene receptor antagonists, such as montelukast sodium; relief of symptoms. Sleeping at night with a scratchy throat and cough, it is recommended that the patient’s hospital visit, after the diagnosis is clear, follow the doctor’s instructions for medication and treatment.