Successful HEN requires a reliable, low-risk (safe), and comfortable route of entry. Frequent or prolonged interruptions in nutritional input due to tubing problems can undermine patient and caregiver confidence and lead to readmissions. Careful consideration should be given to the location of placement and the type of tubing chosen, including the size of the tubing, to minimize complications. When selecting a catheter, physicians need to consider the duration of nutritional support, the type of nutrient solution used, the viscosity, and the amount and rate of input. 1.Placement method: The route of enteral nutrition is gradually developed from the initial single route – nasogastric tube. In recent years, with the development of percutaneous endoscopic placement of gastric/enterostomy tube (PEG/PEJ) surgery, HEN has been further developed. Currently, the main routes are: nasal tube in the stomach, duodenum or jejunum; surgical gastrostomy and jejunostomy; percutaneous endoscopic gastrostomy and jejunostomy; laparoscopic gastrostomy and jejunostomy; X-ray fluoroscopic gastrostomy and jejunostomy. The nasogastric and enteral tube is suitable for short-term (< 6 weeks) use of HEN. nasogastric and enteral tube insertion, surgical, endoscopic, laparoscopic and fluoroscopic gastrostomy or jejunostomy can be performed at home, and is suitable for long-term or lifelong HEN. peg can improve survival, reduce complications such as aspiration, and is more suitable for long-term home enteral nutrition. It has a better appearance. Long-term use of a percutaneous endoscopic gastrostomy can be replaced with a button catheter for better appearance and easier care. Each placement method has advantages and disadvantages, so the physician and the patient should discuss and communicate fully before placement to decide which method to use. 2, the location of the irrigation tube: the location of the irrigation depends on the state of gastric function and the risk of inadvertent reflux. When gastric emptying is impaired, the duodenum or jejunum can be used safely. When there is a risk of reflux, impaired consciousness, or a history of aspiration, the risk of aspiration is high, and duodenal or jejunal insufflation is more appropriate. For patients with high small intestinal fistulas, the feeding tube is sent under X-ray to the distal end of the fistula, using the distal small intestine to digest and absorb enteral nutrition. 3, feeding methods: there are timed push injection (bolus feeding), gravity drip (gravity feeding) and infusion pump drip (pump feeding). Each method has its own advantages and disadvantages, and the time spent, the convenience of activities, costs and the prevention of complications (such as aspiration and diarrhea) need to be considered. The use of infusion pumps is generally recommended for enteral nutrition, especially for the elderly and children at risk of aspiration, patients with gastrointestinal dysfunction, and patients who receive infusions at night. In contrast, the use of infusion pumps is not necessary in young, mobile patients with normal gastrointestinal function.