The small bumps in the middle of the anus and vagina are particularly itchy due to more reasons, considering that it is related to warts, vulvar eczema, gynecological inflammation, etc. The treatment should be based on the cause of the disease through medication, physical therapy and other ways of treatment. 1. warts: this is due to the human papilloma virus infection caused by infectious diseases, with the development of the disease, the vulva can appear localized cauliflower-like or papillomavirus, at the same time can be accompanied by itchy skin, this time can be used in accordance with the doctor’s instructions interferon and other agents to regulate the local immune system, if necessary, can be through the laser or freezing and other physical therapy to destroy the warts. 2. Vulvar eczema: if the vulva localized pimples, vesicles, skin thickening and other polymorphic changes, we should be alert to the occurrence of vulvar eczema, then you can follow the doctor’s instructions to use glycerine lotion, budesonide ointment external coating, if necessary, can be combined with antihistamine preparations such as loratadine oral. 3. Gynecological inflammation: if the patient at the same time combined with increased leukorrhea, it is necessary to vigilant vaginitis, pelvic inflammatory disease, due to the stimulation of local inflammatory factors may also be infected with local hair follicles and the formation of redness and swelling, pain, obvious pimples, at this time need to be used in accordance with the doctor’s instructions bifidobacterium suppositories, nitrofurotol vaginal soft capsules and other preparations for external use, if necessary, need to be combined with the nitrofurotol tablets and other agents for oral administration. The pimples in the middle of the anus and vagina are particularly itchy, there may also be other reasons, it is recommended to go to the regular hospital in time to improve the relevant examination, clear the cause of the disease under the guidance of the doctor targeted treatment. The use of the above medications should be in accordance with medical advice.