The so-called chronic suppurative otitis media is often caused by repeated infections of acute suppurative otitis media that do not heal, but of course there are also other factors, such as chronic inflammation of the nose and pharynx, decreased systemic or local resistance, malnutrition, anemia, etc. The common causative organisms are Staphylococcus aureus, Pseudomonas aeruginosa and Aspergillus. As the disease progresses, the strains become more complex. For example, fungal or drug-resistant species. Therefore, during the acute attack of chronic suppurative otitis media, antibiotics and ear drops can relieve the symptoms, but they cannot solve the fundamental problem.