Itching and ulceration of the toe crevices are commonly caused by local trauma or scratching after insect bites. In addition, it is also often considered to have foot odor, which results in localized itchy ulcers. Patients are advised not to scratch with their hands to avoid aggravating the infected area or causing fungal infection on the hands. Treatment mainly includes oral as well as local topical medication: 1. Oral medication: Itraconazole and terbinafine can be taken orally to treat foot odor caused by fungus. If secondary bacterial infection is applied to antibiotic treatment, such as cephalosporin, erythromycin, etc.. Application of anti-allergy drugs when allergies are induced, such as chlorpheniramine maleate, benadryl, loratadine, etc.; 2. Topical drugs: acute macerated vesicles caused by foot fungus can be dried first with a mild paste or powder, after which boric acid solution and Levanoxyl can be used for wet compresses. After the exudation of vesicles is reduced, topical powder, such as powdered alum, miconazole powder, etc.. After drying, then use antifungal agents, such as clotrimazole, econazole, miconazole, bifenoconazole, etc. If the infection is caused by trauma or mosquito bite after scratching or secondary infection of foot odor, topical antibiotic drugs can be used, including erythromycin ointment, fusidic acid ointment, mupirocin ointment, etc. Topical Chinese medicines can be selected for treatment such as compound Xianglian external lotion, dispel dampness, and Huanglian cream. In addition, patients should keep the ulcer dry at all times to avoid further aggravation of the situation. Patients are advised to avoid eating spicy, stimulating, fatty foods and fishy hair products, such as chili, mutton, fried foods and shrimps and crabs during the treatment period, and they need to quit smoking and alcohol. As foot fungus has a high recurrence rate and is easily infected, patients are advised to pay attention to foot hygiene and avoid sharing foot products with others.