Indigestion may interfere with sleep. Dyspepsia is a syndrome that develops in a variety of disorders. Caused by gastrointestinal dyskinesia, digestive system pathology and mental factors, patients may experience abdominal flatulence, acid reflux and nausea and vomiting during sleep, and the course of the disease is often persistent or recurring, therefore, it may affect sleep. For patients with dyspepsia, it is important to establish good dietary habits in normal life, avoiding spicy and stimulating, raw and cold and greasy food, so as not to aggravate gastrointestinal discomfort. Meanwhile, physical exercise can be increased appropriately so as to promote gastrointestinal peristalsis and secretion of digestive glands and improve the symptoms of indigestion. When long-term indigestion affects sleep, it is recommended to go to the hospital for examination and standardized treatment.