A high serum total bilirubin of 22.9 is also known as subclinical jaundice or hidden jaundice, and whether it is serious or not needs to be judged according to the serum combined bilirubin, symptoms and signs. The normal value of adult serum total bilirubin is 3.4~17.1umol/L. Total bilirubin of 22.9umol/L is high but less than 34.2umol/L, which belongs to subclinical jaundice or latent jaundice, which is not serious only in terms of the value, but the patient’s specific seriousness of the condition needs to be examined by other tests, such as serum conjugated bilirubin, urinary bilirubin, as well as the symptoms and physical signs. Elevated total serum bilirubin should be promptly consulted and treated under the guidance of a doctor, and daily attention should be paid to diet and hygiene, pay attention to rest, avoid exertion, and avoid excessive late-night work.