Prostate biopsy puncture may produce bleeding, infection, urinary tract diseases and other hazards. 1. Bleeding: prostate biopsy puncture may cause bleeding in the prostate, urethra and rectum, so the puncture should be accurately positioned, and the puncture path and needle speed should be reasonably selected to avoid puncturing the urethra, bladder, rectum and other organs. 2. Infection: prostate biopsy may cause infection during the puncture, the surgical instruments and surgical site should be sterilized before the operation, and it is recommended to use ciprofloxacin and other quinolone drugs as prescribed by the doctor for anti-infection before and after the operation. 3. Urological diseases: If the patient suffers from severe prostate hyperplasia, the biopsy may cause prostate congestion and edema, which may lead to urinary retention in severe cases. Patients who need to do prostate biopsy puncture, should go to a regular hospital, under the guidance of the doctor for standardized operation, so as to avoid unnecessary harm to the body.