Currently commonly used rheumatoid arthritis treatment drugs can be classified as: non-steroidal anti-inflammatory drugs, slow-acting anti-rheumatic drugs, biological agents, glucocorticoids. 1, non-steroidal anti-inflammatory drugs: rheumatoid arthritis first-line basic drugs, side effects are small, no drug dependence, generally within a few days to take effect. But the use of this class of drugs alone can not control the progress of the disease. The side effects are mainly gastrointestinal reactions and nephrotoxicity. Representative drugs are: Celebrex, Loxoprofen, Meloxicam, Fotarine, Affin, etc. 2, slow-acting anti-rheumatic drugs: also known as disease-modifying anti-rheumatic drugs and immunosuppressive drugs. As the name implies, this type of drug is slow to take effect, generally need 3 months to be more obvious. This class should also reduce the blood sedimentation, C-reactive protein, rheumatoid factor, anti-cyclic citrulline (CCP) and other indicators to reduce joint destruction. The drugs can affect the autoimmune function of the body, and the possible side effects are increased risk of infection, tumor, and bone marrow suppression, and regular follow-up by a specialist is required during the use of the drugs to adjust the dosage according to the condition. Representative drugs are: methotrexate, leflunomide, hydroxychloroquine, etc. 3, biological agents: can effectively inhibit the body’s inflammatory response, regulate immunity, reduce bone destruction, good effect on rheumatoid arthritis and other autoimmune diseases. Side effects are similar to those of immunosuppressants. Expensive. Representative drugs are: anti-tumor necrosis factor inhibitors, anti-CD20 monoclonal antibodies, interleukin-1 receptor blockers. 4.Glucocorticoids: have anti-inflammatory and immunosuppressive effects. Can quickly control the symptoms, but long-term use can aggravate osteoporosis, joint deformation. Can be used for a short time and in small doses.