Lisfranc teeth are also called wisdom teeth, and there are two reasons for toothache in the process of growing wisdom teeth, on the one hand, it is caused by pericoronitis of wisdom teeth, on the other hand, it is the occurrence of dental caries or pulpitis, apical periapical inflammation of the teeth. In the acute stage, anti-inflammatory drugs, such as cephalosporin and ornidazole, and painkillers, such as ibuprofen, can be taken orally for temporary relief. For toothache caused by wisdom tooth pericoronitis, localized pericoronary rinsing and medication is also required. For caries and pulpitis, root canal therapy is very important and early treatment is recommended. If there is a significant blockage of the wisdom teeth, removal of the wisdom teeth can also be considered after the inflammation is resolved.