Tadalafil can be taken on-demand and daily. The optimal time to take the drug in on-demand dosing is 30 to 60 minutes before sex, while there is no so-called optimal time to take the drug in daily dosing, and patients just need to take the drug regularly. Tadalafil is a drug used to treat erectile dysfunction in men, and its dosing pattern includes both on-demand and daily dosing. Under the condition of on-demand dosing, it is generally recommended to take it 30 to 60 minutes before sexual intercourse. In the case of daily dosing, there is no specific dosing time, as long as the medication is taken regularly. However, regardless of the dosing pattern, it is important to note that the medication should only be taken once a day. The use of tadalafil may cause a number of adverse drug reactions, commonly including flushing, indigestion, back pain, myalgia, and nasal congestion. Tadalafil needs to be contraindicated in people who are taking any form of nitrates. People with a known allergy to tadalafil need to disable the drug. Tadalafil is also contraindicated in people who are using guanylate cyclase stimulators. Tadalafil should not be used by women or adolescents under 18 years of age. Tadalafil should not be used by men whose pre-existing cardiovascular condition does not recommend sexual intercourse. If an erection lasts longer than four hours after using the drug, you should seek emergency medical attention. Individuals should not abuse tadalafil, and the standardized use of tadalafil in accordance with the doctor’s instructions can effectively guarantee the efficacy of the drug and prevent some unnecessary adverse consequences.