Diabetic foot lesions are preventable and treatable, and the goal of dealing with diabetic foot is to prevent the occurrence of foot ulcers and to avoid amputation and reduce the amputation plane at least 50% of amputations in diabetic patients are preventable. Active prevention and treatment can not only significantly improve the quality of life of diabetic patients, but also greatly reduce the related medical expenses. The treatment of diabetic foot is based on good blood sugar control, in addition to the peripheral vascular lesions should be done for specialist treatment, commonly used methods: 1, drug therapy: the main application of vasodilatation, improve microcirculation, nerve nutrition, correction of metabolic disorders, anti-infective drugs. 2, for serious vascular lesions, on the basis of conservative treatment, vascular revascularization should be performed. The methods include: vascular bypass surgery, endarterectomy, percutaneous endoluminal angioplasty (interventional), etc.. Among them, interventional treatment is a minimally invasive procedure, especially suitable for elderly and poor general condition patients, with the characteristics of small trauma, fast postoperative recovery, remarkable efficacy and repeatability, which is the main development direction. 3.Stem cell transplantation: There are mainly two forms of peripheral blood stem cell and bone marrow stromal stem cell transplantation, which are in the initial stage and the main drawback is the inaccurate efficacy.