Drinking alcohol can affect the effectiveness of vaccines. Most vaccines are inactivated pathogens or attenuated pathogens that enter the body after inoculation and stimulate the body’s immune system to produce the appropriate antibodies to avoid being re-infected by the pathogen. Alcohol consumption affects the immune response of the immune system and is detrimental to the production of antibodies in the body. Vaccination itself can have some adverse reactions, drinking alcohol will increase the occurrence of vaccine adverse reactions, such as fever, muscle pain, allergies and other adverse reactions, so do not drink alcohol before or after vaccination. For those who have been drinking heavily for a long time, it is recommended to abstain from alcohol for at least one week. At the same time, try not to eat spicy, stimulating food and special drugs, such as antibiotics, such drugs will also affect the body to produce the corresponding adverse reactions, affecting the production of antibodies.