The term rhinitis actually refers to inflammation of the nasal mucosa, and sinusitis refers to inflammation of the sinus mucosa, and nasal-sinusitis means that there is inflammation of both the nasal and sinus mucosa. Obviously, this is a nomenclature based on the extent of the inflammation affected. Chronic rhinosinusitis, on the other hand, does not only mean that the inflammation affects the nasal cavity and sinuses, but also that it must have reached a certain time and severity. How to define chronic rhinosinusitis based on history, symptoms and signs is certainly important Medical Education Network collection. However, it is difficult to define in the clinic because the patient’s history is often inaccurately described, and the same history varies in terms of symptoms and signs, and the same symptoms and signs can vary. Drug treatment Anti-inflammatory drugs Glucocorticoids (1) intranasal local glucocorticoids: anti-inflammatory and anti-edema effect, the course of treatment is not less than 12 weeks; (2) systemic glucocorticoids: for severe and recurrent nasal polyps, oral prednisone (or prednisolone) can be administered at the recommended dose of 0,5mg/(kg#d), once a day in the morning on an empty stomach, for 5~10 days, up to 14 days. The contraindications to systemic hormone use should be noted, and any possible adverse reactions during the course of administration should be closely monitored. Systemic or intranasal injection of glucocorticoids is not recommended. 2. Macrolides (14-membered ring): They have anti-inflammatory effects and are recommended to be taken orally in small doses (1/2 of the conventional antibacterial dose) for a long period of time for at least 12 weeks [ 1]. Yang Yanzhong, Department of Otorhinolaryngology, Second Hospital of Hebei Medical University 3, antibacterial drugs: penicillins, cephalosporins, sulfonamides, macrolides, fluoroquinolones and other sensitive drugs for acute exacerbations of chronic rhinosinusitis, conventional doses, the course of treatment does not exceed 2 weeks. Topical antibiotics for the nasal sinuses are not recommended. 4. Decongestants: not recommended. Short-term use ( < 7 days) for severe nasal congestion. 5. Mucus promoter: It can dilute mucus and improve cilia activity, recommended. 6. Systemic antihistamines: For patients with allergic reactions, the 2nd generation or new antihistamines can be taken orally. 7. Chinese medicine: Some Chinese medicines are effective in improving the symptoms of chronic rhinosinusitis, and should be selected according to the principles of evidence-based treatment. 8. Physiological saline or hypertonic saline (2%~3%): used for nasal rinsing.