Soreness at the bottom of the throat may be caused by upper respiratory tract infection, acute epiglottitis, acute laryngitis and other diseases. 1. Upper respiratory tract infection: caused by cold and flu viruses, such as rhinovirus, parainfluenza virus infection, there can be coughing and coughing up phlegm, pain in the throat and the lower part of the throat, fever and headache and other symptoms. 2. Acute epiglottitis: acute inflammation of the laryngeal mucosa in the epiglottis below the throat, mainly in the supraglottis area, often with a more acute onset, with symptoms such as sore throat, difficulty swallowing, fever, etc., and in severe cases, it can cause asphyxia. 3. Acute laryngitis: acute respiratory disease caused by inflammation, decreased immunity or excessive vocalization. There can be hoarseness, laryngeal pain, increased laryngeal secretions and other manifestations of the general adult symptoms are mild, children are more serious. If you have a sore throat, you should go to the hospital in time for diagnosis and treatment.