Hiccups are also known as eructations. The common causes of hiccups include physical and chemical irritants, digestive diseases such as esophageal cancer, gastroesophageal reflux and gastrointestinal bleeding, and intracranial diseases such as glioma and optic neuromyelitis optica. 1. Physical and chemical irritating factors: such as eating too fast, eating too much, emotional excitement, eating stimulating food leading to spasmodic contraction of diaphragm. 2. Digestive diseases: such as esophageal cancer, gastroesophageal reflux, gastrointestinal bleeding and other diseases that stimulate the vagus nerve and the phrenic nerve, which can cause the symptoms of hiccups. Acid-suppressing drugs such as omeprazole can be taken as prescribed by doctors to inhibit the secretion of gastric acid; gastrointestinal stimulants such as domperidone can also be taken to increase the pressure of lower esophageal sphincter, improve the function of esophageal peristalsis and promote gastric emptying. Tumor diseases need to be treated with surgery or radiotherapy. 3. Intracranial diseases: such as glioma, optic neuromyelitis optica, brain tumors, etc. may have frequent symptoms of hiccups. There may be other causes of hiccups. If the above symptoms occur repeatedly, it is recommended to go to the hospital for diagnosis to avoid delay.