HFMD is an acute febrile rash disease caused by enterovirus infection, and there are several signs for evaluating the improvement of HFMD: 1) body temperature gradually returns to normal; 2) the child’s symptoms of oral pain are significantly reduced, appetite is restored, and no further aggravating symptoms such as nausea and vomiting are present; 3) there are fewer new rashes in patients with HFMD; 4) other systemic symptoms are significantly reduced, such as Respiratory symptoms, such as coughing, and neurological symptoms, such as convulsions, limb shaking; 5, the gradual recovery of digestive function, manifested in the child’s appetite increased significantly, the gradual disappearance of gastrointestinal symptoms. If there are these situations, it is basically to the good side.