The burning sensation in the stomach is mostly considered to be caused by gastroesophageal reflux disease (GERD), peptic ulcer, chronic gastritis and so on. 1. Gastroesophageal Reflux Disease (GERD): GERD refers to the reflux of duodenal and gastric contents or duodenal fluid into the stomach and esophagus, causing irritation to the mucous membrane of the stomach and esophagus, which results in symptoms such as acid reflux, belching, and burning sensation in the stomach. 2. Peptic ulcer: it is caused by the mucous membrane of gastrointestinal tract being digested by gastric acid and pepsin under certain circumstances, which is mainly manifested as pain in the epigastric region, increased salivation, regurgitation, burning sensation and other symptoms. 3. Chronic gastritis: irregular meals, late-night snacking and other unhealthy habits, disturbing the normal digestion and absorption function of the stomach, so that excessive secretion of gastric acid, promote gastric disease, the main symptoms of abdominal pain, acid reflux, burning sensation, loss of appetite. When patients eat and feel a burning sensation in the stomach, it is recommended that they should seek medical attention in a timely manner to clarify the cause of the disease and then treat it.