Women’s menopausal cold and hot is mainly related to the decline of ovarian function, estrogen secretion decrease, caused by vegetative nerve disorder, this situation can be according to the doctor’s advice to take estrogen supplements, glutamine and other drugs to regulate. Menopausal women who are hot and cold need to improve the estrogen level deficiency and plant nerve disorder in time. If there is no contraindication to take estrogen supplements, such as uterine fibroids, breast tumors, etc., you can take estrogen supplements such as estradiol valerate tablets according to doctor’s instructions, and you can also take glutamine orally to improve the symptoms of vegetative nerve disorder. In menopause, women should pay attention to the regularity of life, and can be appropriate for physical exercise. At the same time, we should also enrich the content of life and keep a good mood. It should be noted that menopause estrogen supplementation should be carried out under the guidance of a doctor, the dose and medication should be individualized, to the minimum dose, to achieve optimal efficacy for the best. It is recommended that the use of any drug need to follow the doctor’s instructions, do not self-medication, so as not to delay the condition.