There are physiologic and pathologic reasons for gallbladder enlargement. Physiologic reasons are that the gallbladder is enlarged when the patient does not eat, and this is the resting state of the gallbladder, which usually shrinks and diastoles when the patient eats. If you consider a pathologic enlargement of the gallbladder, it means that the gallbladder has inflammation or stones that cause bile duct obstruction. The enlarged gallbladder may cause indigestion, abdominal pain, abdominal distension, and even jaundice and pancreatitis caused by stone discharge, etc. It is necessary to identify the cause of the disease, check the imaging and liver function to identify the cause of the enlarged gallbladder, and take corresponding treatment. In most cases, gallbladder stones are considered to cause biliary obstruction, and biliary tract tumors or gallbladder tumors must also be excluded, so that early detection of lesions can be treated at an early stage.