A small white blister on the edge of the eye, depending on the location, may be vesicular conjunctivitis, eyelid blepharitis, and skin acne. 1. A small white blister on the edge of the pupil of the eye surface is likely to be vesicular conjunctivitis, usually accompanied by symptoms of conjunctival congestion. It is recommended to use saline to rinse the conjunctival sac, topical drops of hormone eye drops such as prednisolone acetate treatment, after a period of time the symptoms improve. 2. Due to late night, blepharitis and other blepharospasm caused by the blockage of the blepharospasm, making the oil discharge is not smooth, which leads to chronic inflammation of the blepharospasm, manifested as a small white blisters on the eyelids, it is recommended that early hot compresses, apply antibiotic ointment such as levofloxacin. 3. In the skin around the eyes grew a small white blister, consider due to the oil secretion caused by the skin acne, usually contains pus, it is recommended to apply metronidazole gel, adapalene gel anti-inflammatory disinfection, to promote the acne subside. It is recommended to rest more, pay attention to the eye surface hygiene, the emergence of serious small white blisters or to go to the hospital ophthalmology timely consultation.