ERCP stone extraction pain, we can imagine a 1.5cm thick mirror through the patient’s mouth, for half an hour or even an hour and a half to two hours of surgical operation, the patient pain in that case, mainly because there is nausea, vomiting reaction heavy. But now with the improvement of the surgical level, the general surgery can be solved within half an hour. For sensitive patients, a painless approach can be taken to operate on the patient. In some places, almost all patients are operated under intravenous anesthesia, and some are even operated under tracheal intubation conditions, where the patient’s pain is certainly small or even painless, but this method increases the risk of intravenous anesthesia, so for some patients, it is important to weigh which method is safer and which surgical method is adopted to give the patient safer treatment.