There are six major classes of drugs for the treatment of hypertension, each with its own characteristics, and their side effects are as follows: 1. diuretics: the most common side effect is malaise. Because diuretics drainage, potassium and sodium, electrolyte disorders may occur after malaise, but the incidence is small; 2, beta-blockers: hypertension accompanied by increased heart rate is more appropriate for patients to apply. Individual patients may experience weakness after taking them; 3, calcium antagonists: more applications, such as Loxodren, Bison and other drugs. A small number of patients may experience flushing, panic, swollen feet and other side effects after taking them; 4, ACEI and ARB: very few people may experience dry cough or edema after taking ACEI, and ARB drugs have relatively few side effects; 5, alpha-blockers: not as the first-line antihypertensive drugs, but may be used for refractory hypertension. The most common side effect is postural hypotension, but the incidence is relatively small. These are the six major types of side effects of antihypertensive drugs, patients do not need to worry, most of them are safe.