Patients with hypertension who cannot lower their blood pressure to normal by taking antihypertensive drugs may be caused by unsuitable types or insufficient amounts of antihypertensive drugs, and many may also be caused by refractory hypertension, which means that patients who cannot bring their blood pressure up to the standard even after applying three or more antihypertensive drugs, or applying four or more drugs to bring their blood pressure up to the standard, are considered to have refractory hypertension. For the former case, patients mainly go to the regular cardiology hospital to adjust the antihypertensive drugs, patients mainly on the basis of antihypertensive drugs to actively improve bad habits, to find the cause, especially some young people may be due to secondary hypertension, this situation is not good antihypertensive drugs, patients must exclude renal insufficiency, renal artery stenosis and other reasons caused by Patients must rule out renal insufficiency, renal artery stenosis and other causes of secondary hypertension, and standardize treatment.