The optimal time for treatment of pulmonary embolism should be early diagnosis and early intervention, and the time window for thrombolysis of pulmonary embolism is usually within 14 days for thrombolysis. The principle of management of acute pulmonary embolism is that it should be diagnosed early and treated early, and highly or suspected diagnosed acute pulmonary embolism should be closely monitored and anticoagulated to prevent recurrence and formation of thrombus, mainly with common heparin. Thrombolytic therapy should also be administered within 14 days, which should be done cautiously and can be prolonged appropriately if there is a trend of new acute pulmonary embolism. Commonly used drugs for thrombolysis include urokinase. Pulmonary embolism should be timely consultation, according to the degree of risk to choose the appropriate treatment program, detection of respiration, heart rate, blood pressure and electrocardiogram changes, etc., daily attention to rest, avoid staying up all night. Drugs need to be used under the guidance of a doctor, avoid self-medication.