First, the application of staining and magnification endoscopy has brought endoscopy into the “microscopic era”. It is understood that the diagnosis rate of conventional endoscopy for early gastrointestinal tumors is 10-15%, but the new technology of staining and magnifying endoscopy can improve the diagnosis rate of early cancer by more than 30-50%. Professor Yao Liqing told reporters that the structure and principle of magnifying endoscopy is not essentially different from that of ordinary endoscopy, but it can be magnified 60 to 170 times. With this major change, endoscopists can easily see lesions that could not be observed before. In 2006, Zhongshan Hospital was the first in China to perform ESD surgery and has completed more than 5,000 cases since then, making it one of the earliest and most completed endoscopic procedures in China, as well as training nearly 500 endoscopic diagnosticians across the country. In recent years, the development of endoscopic diagnostic and therapeutic techniques at Zhongshan Hospital has provided a powerful weapon for diagnosing early-stage cancers of the digestive tract, and is expected to provide useful help to improve the diagnosis and treatment of digestive tract cancers in China. Thirdly, there is a significant innovation in the joint treatment of submucosal tumors of the digestive tract by “dual-scope”. The so-called “dual-scope” combined treatment refers to the laparoscopic-assisted endoscopic resection technique, which provides a good method for complete resection of “smaller lesions” in the submucosa of the gastrointestinal tract, but for some larger submucosal tumors that required surgery in the past, endoscopic and laparoscopic resection techniques are now available. However, for some larger submucosal tumors of the gastrointestinal tract that previously required surgery, the combined endoscopic and laparoscopic treatment now provides a new minimally invasive treatment method for patients. Larger submucosal tumors of the gastrointestinal tract can be completely removed under laparoscopic surveillance using endoscopic techniques, followed by laparoscopic repair and placement of abdominal drainage. The patient only needs to make 3 or 4 small holes in the abdomen, which completely avoids the pain of opening the abdomen in the past and has the advantages of safety, minimally invasive and effective. Fourth, “transoral endoscopic sphincterotomy” (POEM) has become the first choice for the treatment of cardia incontinence, and patients do not need open-heart surgery. Associate Professor Zhou Pinghong said, “Cardia achalasia is the most common esophageal motility disorder, which is characterized by difficulty in eating, weight loss, postprandial regurgitation, nocturnal choking and retrosternal discomfort or pain. The traditional radical treatment requires open-heart surgery and muscle dissection of the lower esophagus, but this method is painful for the patient, has a long hospital stay and is costly. However, in recent years, the endoscopy center of Chinese medicine hospital has used the new “endoscopic transoral sphincterotomy” to save patients from the pain of open-heart surgery. Associate Professor Zhou Pinghong told reporters that this surgery is very clever, it is under the gastroscope in the patient’s esophagus to open a “window”, through this “window” to the lower part of the esophagus and the cardia area of the circular muscle cut, to achieve similar treatment results as open-heart surgery, and then finally The “window” is closed through endoscopic techniques. The patient can eat the next day, and it has the advantages of safety, effectiveness, less pain, shorter hospital stay and lower cost. At present, the endoscopy center of Zhongshan Hospital has completed more than 50 cases with excellent results, and patients from all over the country are coming to the center, and the hospitalization time is only 2 or 3 days, which greatly reduces medical costs and is well received by patients.