Endometrioid adenocarcinoma clear cell carcinoma stage 1A can be treated with surgical treatment, radiotherapy treatment, etc. If available, DNA testing can be considered. Endometrial clear cell carcinoma is a type II endometrial cancer and stage 1A is an early stage of endometrial cancer. Endometrial cancer is an epithelial malignant tumor originating from the endometrium and is hereditary. The most important test for hereditary endometrial cancer is DNA mismatch repair gene mutation, so endometrioid adenocarcinoma clear cell carcinoma stage 1A requires DNA testing. Endometrioid adenocarcinoma clear cell carcinoma stage 1A is mainly treated by total hysterectomy with double adnexectomy, or pelvic and para-aortic lymph node dissection. Depending on the results of pathologic examination, some patients need to be combined with radiation therapy or chemotherapy, which is more effective in treatment and has a lower recurrence and metastasis rate and a higher survival rate. Patients with endometrioid adenocarcinoma clear cell carcinoma stage 1a are advised to have timely examination and treatment and regular postoperative review, and to seek immediate medical attention when discomfort occurs.