Eplazole and bismuth potassium citrate can be used in combination for the treatment of gastroduodenal ulcers.
Eprazole is a proton pump inhibitor that selectively enters the cells of the stomach lining and inhibits gastric acid secretion after oral administration. The main adverse effects are diarrhea, headache and elevated transaminases. Because of the strong acid inhibiting effect of this drug, it should not be taken for a long time for people with general peptic ulcer.
Bismuth potassium citrate is a kind of gastrointestinal mucous membrane protector, which can form many forms of insoluble complexes under acidic environment and deposit on gastric mucous membrane to protect the mucous membrane. It is suitable for chronic gastritis, gastric ulcer and other diseases. During drug administration patients may have black tongue and stool, and some patients may experience adverse reactions such as nausea, vomiting and dizziness.
In the presence of eprazole and bismuth potassium citrate respective indications can generally be combined use of the two drugs, but need to be standardized under the guidance of a doctor to avoid adverse consequences.