Tick bites can be further analyzed on the basis of clinical manifestations or through serological and pathogenetic tests. 1. Clinical manifestations: Ticks are small spiders that attach to the skin and feed on blood after biting, resulting in flu-like symptoms. For example, muscle pain, fever, nausea and vomiting, headache, skin rash and other adverse reactions, and in more serious cases, patients may also show allergic reactions. 2. Serologic examination: patients can also be further clarified by serum specific antibody test, if the patient’s serum antibody in the recovery phase is at least 4 times higher than that in the acute phase, it can be determined as tick bite. 3. Pathogenetic examination: whole blood or blood cell specimens can also be used for PCR under the guidance of the doctor, and if the specific nucleic acid of the pathogen is positive during the test, it can be determined as a tick bite. If a patient suspects a tick bite, he or she should go to the local hospital in time for early detection of the problem and early treatment.