Singing generally has no effect on thyroid nodules. People with thyroid nodules need to seek medical attention and maintain good lifestyle habits. The vocal tissues and organs needed for singing include the trachea, vocal cords, lungs, diaphragm, mouth, and pharyngeal isthmus, which do not require the involvement of the thyroid gland. Anatomically, the thyroid gland consists of the isthmus of the thyroid gland and two lateral lobes on either side. Among them, the location of the thyroid isthmus is usually in front of the 2nd to 4th tracheal cartilage, and the upper edge of the two lateral lobes is usually flat thyroid cartilage, and the lower edge is mostly located in the 5th to 6th tracheal ring. Vibration of the vocal cords during singing can lead to vibration of the thyroid gland, but this vibration does not stimulate the growth of thyroid nodules. In addition, thyroid nodule patients who do not have pressure symptoms such as difficulty breathing or swallowing due to the large size of the nodule, and who do not experience discomfort such as pain, will not be affected by speaking or singing. Patients with thyroid nodules need to seek timely medical attention and standardized treatment under the guidance of a doctor.