Bile acid 16 μmol/L in pregnant women is a little on the high side, but not serious. The normal value of bile acid in pregnant women is below 10 μmol/L, which is categorized into physiological elevation and pathological elevation. Physiological elevation refers to pregnant women during pregnancy bile acid level more than 10 μmol / L, but less than 40 μmol / L situation, this is due to the burden of liver function during pregnancy, generally more rest, improve diet, such as eating a light diet, reduce greasy and high-sugar food intake can be relieved. Pathological elevation of bile acids is defined as bile acids higher than 40 μmol/L, suggesting that the presence of intrahepatic cholestasis in pregnancy is very likely, which may lead to more serious adverse pregnancy, affecting the health and life of the fetus, and requires drug treatment, such as ursodeoxycholic acid. Pregnant women with bile acids 16 μmol measured during pregnancy must be aware of dietary and lifestyle changes. In addition, regular monitoring, if persistently elevated, should be promptly treated with medication to avoid delays.