Sitting up on both sides of the thigh and lumbar muscle pain, the cause may have lumbar muscle strain, myofasciitis, lumbar intervertebral disc herniation compression of the nerves, etc., and its treatment includes general treatment, physical therapy, drug therapy, surgical treatment, etc.. 1. Lumbar muscle strain: in this case, it is recommended to rest more, reduce the time of sitting and standing, or sitting on a stool with a soft cushion. Can also be appropriate hot compresses, with massage, massage and other physiotherapy, relaxation of the muscles, help to relieve the symptoms of localized soreness. When there is obvious pain, you can use celecoxib, ibuprofen and other non-steroidal anti-inflammatory drugs to relieve pain, you can also use ethopiridone and other antispasmodic muscarinic drugs, or topical diclofenac diethylamide cream agent. 2. Myofasciitis: most people after rest, the symptoms can be relieved, can also be localized physical therapy and massage, etc.. When the pain is obvious, the above non-steroidal anti-inflammatory drugs and antispasmodic myorelaxants are also applicable. Localized closed treatment can also be used. 3. Lumbar disc herniation compression of nerves: you can relieve the symptoms through localized hot compresses, professional massage, acupuncture, tuina and other physiotherapy, you can also take nimesulide, diclofenac sodium, etc. to relieve the pain, can be combined with nutritive drugs, such as methylcobalamin, etc. for treatment. In severe cases, surgery can also be considered. The above medications should be used under the guidance of a doctor. When the above symptoms occur, it is recommended to consult a doctor in time and receive standardized treatment to avoid delaying the condition.