Pain inside the ear and pus indicates that the patient has acute otitis externa or acute suppurative otitis media, and it is best to go to the hospital to check whether the eardrum is perforated. If it is simple otitis externa, it is better to treat it. Patients can clean their ears with hydrogen peroxide and then use levofloxacin hydrochloride ear drops to reduce inflammation. If the patient has a perforated eardrum, antibiotics can be added to prevent infection. Cefixime tablets are commonly used, and a clear allergy history is needed before using the medication. Patients also need to clean the ear canal with hydrogen peroxide, and then apply lomefloxacin hydrochloride ear drops to consolidate the anti-inflammation. It is important to keep the ears clean and avoid water and trauma. Especially after a cold, patients should not blow their noses to avoid triggering otitis media or even tympanic membrane perforation.