China is the world’s largest producer, consumer and victim of tobacco, with 350 million smokers, and 1 million deaths from tobacco-related diseases each year, more than the total number of deaths from AIDS, tuberculosis, traffic accidents and suicide combined, accounting for 12% of all deaths, and expected to rise to 33% by 2020. Tobacco use is a major cause of many diseases of the respiratory, cardiovascular, and digestive systems. Tobacco can damage almost all organs of the body, and smoking-related diseases and lesions include hypertension, coronary heart disease, stroke, chronic obstructive pulmonary disease, asthma, cancer (including tumors of the lungs, lips, mouth, nose, throat, larynx, esophagus, stomach, liver, kidneys, bladder, pancreas and cervix), peptic ulcer, thrombo-occlusive vasculitis, impotence, aortic aneurysm, peripheral vascular disease, granulocytic leukemia cataracts, clone disease, hip fractures, periodontal disease, etc. Most respiratory diseases are closely related to smoking, which is the main cause of chronic obstructive pulmonary disease and is the main culprit of lung cancer. Investigations show that smoking causes 45% of deaths from chronic obstructive pulmonary disease, lung cancer accounts for 15%, esophageal cancer, stomach cancer, liver cancer, stroke, coronary heart disease and tuberculosis accounted for 5% to 8% each. The greater the amount of smoking, the longer the duration of smoking, and the earlier the age at which smoking begins, the greater the risk of smoking-related disease and death. Because the health damage caused by smoking is characterized by a long-term lag, with diseases associated with smoking taking 10, 20 or more years to appear, smokers often do not recognize the dangers of smoking until the disease appears. Cigarette smoke is a complex mixture of more than 4,000 compounds, consisting of volatiles present in the gas phase and semi-volatiles and non-volatiles present in the particles, of which gases account for 95%, such as nitrogen, oxygen, carbon monoxide, carbon dioxide and hydrogen cyanide, volatile nitrosamines, hydrocarbons, ammonia, volatile sulfides, nitrile, phenols, aldehydes, etc.. Another 5% are particulate matter, such as tobacco tar, nicotine (nicotine), etc. Among these compounds, nicotine is the substance that causes addiction, and tobacco tar, carbon monoxide, hydrocyanic acid, ammonia and aromatic compounds are the main toxic substances, of which at least 69 are known carcinogens. Basic attitudes toward tobacco control are an important reflection of how civilized a society is. The direct and indirect effects of quitting smoking are clear. First, quitting reduces the incidence of and death from many diseases, including stroke, peripheral vascular disease, chronic obstructive pulmonary disease (COPD), pneumonia, and gastric and duodenal ulcers. Quitting smoking at all ages is beneficial, and quitting before age 30 reduces the risk of lung cancer by 90 percent. Five years after quitting, the increased risk of oral and esophageal tumors due to smoking is reduced by half. The risk of heart disease decreases even more rapidly after quitting, with deaths from smoking halved within 1 year and the absolute risk similar to that of never-smokers within 15 years. Smoking accelerates the rate at which lung function decreases with age, and quitting increases lung function mildly, reversing the rate at which it decreases. Regardless of when they quit, smokers who quit will live longer than those who continue to smoke. Quitting early is better than quitting late, and quitting is better than not quitting at all” means that those who quit early can add more years to their lives than those who quit late, and the years of life added by quitting are “healthy years of life. Quality of life. Second, quitting reduces the risk of passive smoking to those around them, especially their family members and coworkers. The act of quitting smoking can also serve as a model for family, friends, and co-workers, especially in influencing the attitudes of youth toward smoking. There are also clear economic benefits to quitting. However, quitting is not an easy task for smokers because of nicotine dependence, the essence of smoking addiction is nicotine dependence. Nicotine is an alkaloid first extracted from tobacco in 1828, nicotine is very easily absorbed by the oral, gastrointestinal and respiratory mucosa. Ninety percent of inhaled nicotine is absorbed in the lungs, and a quarter of it enters the brain within a few seconds. The most significant effect of nicotine on the human body is the effect on the sympathetic nerves, which can cause respiratory excitement and increased blood pressure; it can make smokers feel joyful, agile, brain power, reduce anxiety and suppress appetite. Large doses of nicotine can have an inhibitory effect on the vegetative nerves, skeletal muscle motor end plate cholinergic receptors and the central nervous system, resulting in respiratory muscle paralysis, impaired consciousness, etc. Long-term inhalation can lead to decreased vitality, memory loss, low work efficiency, and even cause a variety of organs involved in a comprehensive pathology. The greatest harm of nicotine is addictive, smokers once addicted, every 30 to 40 minutes you need to smoke a cigarette to maintain a stable level of nicotine in the brain, when the level is not reached smokers will feel irritable, discomfort, nausea, headache and desire to replenish nicotine, tobacco dependence is also known as nicotine dependence. A considerable number of smokers have the phenomenon of tobacco dependence, and once they quit smoking will experience a series of maladaptive symptoms, for nicotine withdrawal symptoms, related to withdrawal syndrome, making “old smokers”, fear of quitting. Tobacco dependence is also closely related to the social environment, psychological factors and genetic factors, tobacco dependence is a chronic disease, and WHO has included tobacco dependence as a disease in the International Classification of Diseases. Therefore, smoking cessation should be treated as a disease and requires professional skills to assess, intervene, and treat tobacco-dependent individuals in a professional manner (including behavioral therapy and medication). During the cessation process, the physician investigates the smoker’s smoking status, asks the patient about his or her smoking status and assesses his or her desire to quit. Clinical interventions by physicians can be effective in reducing the incidence of disease, preventing death, and improving quality of life. With the worldwide implementation of the Framework Convention on Tobacco Control (FCTC) and the introduction of national regulations banning smoking in public in the European Union, China has also prepared legislation to designate no-smoking areas in the public sphere. the World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) entered into force in China in January 2006. In order to fulfill the FCTC, promote smoking cessation services in China, and establish a standardized, professional, and scientific approach to medical smoking cessation, our country has developed the 2007 edition of the Chinese Clinical Guidelines for Smoking Cessation. As a member of the writing group and expert group for the 2007 Edition of China Clinical Quit Guidelines, Sun Yongchang, director of our respiratory department, provides scientific and standardized professional guidance for our smoking cessation clinic as a domestic clinical medical expert in tobacco control. It is the duty of respiratory doctors to apply scientific and standardized methods to help smokers quit smoking, free them from tobacco dependence and effectively prevent diseases. In order to fulfill the sacred duty of doctors to protect the rights and interests of human health, the respiratory department of our hospital is open to all smokers in the whole society. We believe that smoking cessation will receive more and more response and will have a huge social effect, freeing tens of thousands of smokers from the trap of cigarettes.