Blisters are generally referred to as blisters, and small blisters on the soles of the feet may be caused by ringworm of the feet, herpes sweat and palmoplantar impetigo and other diseases. 1. Tinea pedis: the onset of tinea pedis is mostly related to pathogenic bacterial infections, hot and humid environments, impaired immune function may also trigger the disease. The patient’s local skin will appear keratinized scales, peeling, blisters and other symptoms. 2. Sweat herpes: the etiology of sweat herpes is not yet clear, may be related to local allergies, dermatophyte infection and other factors, mainly manifested as itchy deep blisters on the hands or feet. 3. Palmoplantar pustulosis: the onset of palmoplantar pustulosis may be caused by localized infections, heredity, smoking and other factors. The main manifestation is the appearance of aseptic pustules on the palms of the hands or soles of the feet. There are many diseases that cause small blisters on the soles of the feet, and it is recommended that patients seek medical examination to clarify the cause of the disease.