Membranous nephropathy can not be cured within 3 to 5 years, but a small number of clinical manifestations of membranous nephropathy have a tendency to spontaneous remission. Patients with membranous nephropathy are mainly characterized by massive proteinuria, edema, hypoproteinemia, hyperlipidemia, etc. The disease is an autoimmune disease, which is generally not able to be cured by itself within 3-5 years, and cannot be completely cured. Some patients, especially patients with membranous nephropathy with proteinuria in the range of nephropathy, have a tendency to spontaneous remission, and a small number of patients can have proteinuria turn negative, but this is not a complete cure for the disease, and there is still the possibility of relapse. Most of the patients with membranous nephropathy need to be treated with glucocorticoid and other immunologic agents, which can reduce or even turn the urine protein into negative, and achieve clinical cure, but still need long-term continuous treatment. Although membranous nephropathy cannot be completely cured within 3-5 years, the decline of renal function will be greatly slowed down after proteinuria becomes negative, so it is recommended that patients under the guidance of physicians for active treatment.