How to treat meningeal metastases

Meningeal metastases are mainly for brain metastases. Brain metastases are the most common brain tumors in clinical practice, and their treatment advice is largely based on their clinical condition. If the primary lesion is unknown or undiagnosed, its treatment recommendations, for almost all patients, consider surgical resection or stereotactic biopsy. When uncontrolled widespread systemic metastatic cancer with significantly shorter life expectancy or poorer physical status is present, treatment is based on biopsy plus whole-brain radiation therapy. For single metastases, if symptomatic, large or reachable site lesions, treatment is based on surgical resection plus whole brain radiotherapy; for single metastases, asymptomatic, small or inaccessible site lesions, whole brain radiotherapy with increased dose stereotactic radiosurgery is recommended. For multiple metastases and treatment, if one of the large lesions is life-threatening or causes a space-occupying effect, treatment is based on surgical resection plus whole-brain radiotherapy for the remaining lesions.