What is immunization? The word “immunization” comes from the Latin word “immunis”, which originally meant “exemption from charges”, but also included the meaning of “freedom from disease”. The original meaning was “exemption from charges”, which also includes the meaning of “freedom from disease”. The modern concept of immunity, immunity for the body to identify and exclude antigenic foreign body physiological function, is a protective physiological response of the body. Its role is to identify “themselves” and “non-self”, to exclude antigenic foreign matter, in order to maintain the relative stability of the body’s physiological functions. Immunity is the body’s own defense mechanism, is the body to identify and destroy foreign invasive foreign matter (viruses, bacteria, etc.), dealing with aging, damage, death, degeneration of their own cells, as well as identifying and dealing with the body’s mutant cells and virus-infected cells. Under normal conditions, this physiological function is beneficial to the organism and can produce anti-infection, anti-tumor and other immunoprotective effects that maintain the physiological balance and stability of the organism. Under certain conditions, when the immune function is dysfunctional, it can also produce harmful reactions and results to the organism, such as allergic reactions (e.g., pollen allergy, penicillin allergy, etc.), autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, etc.) or immunodeficiency diseases (e.g., AIDS) and so on, and decreased immunity (e.g., recurrent colds and flu, etc.), which can damage the health of the organism. Immunity is divided into non-specific immunity and specific immunity. Non-specific immunity refers to a certain degree of resistance to all pathogenic microorganisms, without special selectivity. It is also known as natural immunity or innate immunity. Such as the barrier effect of skin and mucous membranes, the blood-brain barrier, the barrier effect of the placenta, etc.; the phagocytosis of phagocytes (neutrophils in the blood and macrophages in the tissues) and the bactericidal effect of bactericidal substances (lysozyme, etc.). Specific immunity refers to the specific resistance of the body against a certain type or class of microorganisms or their products, including humoral immunity and cellular immunity. Humoral immunity mainly refers to the immune process of antibody production through B lymphocytes. For example, bacterial exotoxin that enters the body binds to the antitoxin (an antibody) in the body to make it lose its toxicity, and after a virus invades the body, the antibody binds to the antigen (virus) to make the virus inactive and unable to invade the cells. Cellular immunity mainly refers to the process of immune response through T-lymphocytes to play an immune role, effector T-cells and antigen invaded host cells (i.e., target cells) close contact, activate the lysosomes in the target cells, so that the target cell membrane permeability changes, osmotic pressure changes, and ultimately lead to the death of the target cells. How does Chinese medicine recognize immunity? Chinese medicine has a long history of recognizing immunity, as early as in the Yellow Emperor’s Classic of Internal Medicine (Huang Di Nei Jing). The four qi and God’s Great Theory” that is: “Therefore, the sages do not treat the already sick to treat the disease, do not treat the already chaotic to treat the not yet chaotic,” the exposition, in fact, created the world’s antidote to the precedent of medical science. China’s ancient Eastern Jin Dynasty Ge Hong in the “after the elbow to prepare the emergency formula” recorded the use of rabies brain compresses to cure rabies method. Ge Hong’s preventive and curative measures against rabies can be regarded as the pioneer of immunology in the world. During the Ming Dynasty, the human pox inoculation method – the “nasal vaccine method” – was widely used to prevent smallpox. This is the earliest treatment method of artificial immunization in the world. Suwen zhi zhuan (The Remains of Suwen) The Theory of Assassination Method” says: “When positive energy is stored inside, evil cannot be dried up, and where evil comes from, its energy will be weak”. Chinese medicine discusses the leading ideas of modern immunology in simple language. Positive qi represents the body’s ability to defend and resist disease and evil, and the struggle between positive and evil is universally applicable to the process of the onset, development and termination of disease. The doctrine of Zhengqi in Chinese medicine is equivalent to the doctrine of immunology in modern medicine, and from the perspective of disease resistance, the meanings of the two concepts of Zhengqi and human immunity are basically the same. According to Chinese medicine, positive qi refers to the basic substances and physiological functions of the human body that resist disease and evil and maintain normal life activities. In nature, there are harmful pathogenic microorganisms and other toxic and harmful substances, which is called “evil qi” in Chinese medicine. The reason why people do not develop diseases is that the human body has the ability to adapt to the influence and changes in the external environment, i.e. “positive qi”. Positive qi is drawn from the kidneys and relies on the essence of the kidneys, which is nourished by the essence of the water and grains in the latter day and the clear qi of nature. Immunoregulation is the strength of Chinese medicine. In Suwen zhengqi tongtian lun, it is said, “When the yin is calm and the yang is secret, the spirit is cured”. If our body is maintained in a state of immunity with a balance of yin and yang, i.e., a state of “yin and yang secrecy,” we will be healthy and free from disease. Once yin and yang are out of balance, it will lead to immune disorders. Therefore, any immune disease should be treated mainly by adjusting yin and yang. This kind of adjustment belongs to the overall regulation, which often has a two-way regulatory effect. The immunoregulatory effect of Chinese medicine is mainly manifested in the following: there is no obvious effect on the normal organism, but there is a significant effect on the immune dysfunction organism; the hyper suppression, the trap lifting, the strong folding, the weak relief. That is, through the regulation of yin and yang, qi and blood, internal organs, etc., to correct the body too low or too high immune state, so that it restores and maintains immune stability; can enhance the normal body’s immune system, but also to get rid of the disease-causing factors, and at the same time play a positive and eliminate the opposite of the role of the opposite of the role of the evil. Immune-regulating and suppressing traditional Chinese medicines include: bitter ginseng, rhubarb, yellow dock, cypress, scutellaria baicalensis, comfrey, shengdi, xuanshen, maitong, asparagus, cocos, yujin, curcuma, Lonicera japonica, white fresh skin, bitter bean root, etc.