1. Appropriate drug therapy. Studies have shown that disability in patients with optic neuromyelitis optica is caused by recurrent relapses, and it is now clear that immunosuppressants have a role in preventing relapses. These drugs include hormones, azathioprine, mortezaprine, etc. Most of them belong to oncological chemotherapy drugs and have high side effects, thus they must ask a professional doctor to personalize the drug selection and program development for the patient. At present, we can help to select drugs according to the patient’s condition, economic status and genetic precision examination. We can monitor blood drug concentration, serum specific antibody titer, etc., and judge drug toxicity and efficacy by combining with clinical score. 2, can intermittently apply B vitamins to nerve nutrition, emphasizing the application of allopathic drugs to reduce increased muscle tone, painful spasms, cognitive dysfunction, etc. 3, patients are prone to anxiety and depression during the course of the disease, and must be treated actively and early. Because anxiety and depression not only affect the mood, affect the effect of rehabilitation and exercise, but also lead to sleep disorders, immune endocrine system disorders, and even self-harm and suicidal behavior. 4, it is recommended to apply some adjuvant medication under the guidance of a doctor to reduce the side effects of hormones and immunosuppressants. 5, to adhere to scientific exercise, improve the overall state of the body, for patients with neurological dysfunction is recommended to combine with physical rehabilitation. 6.Avoid exertion, emotional excitement, and rest immediately when feeling tired; avoid or actively treat fever, cold and diarrhea; avoid live vaccination; avoid long-term exposure to high temperature environment, such as fever, tropical travel, hot bath, hot spring, sauna, etc.; pay attention to physical changes and continuously record the onset; develop exercise habits, moderate, regular and persistent exercise, and for patients with movement disorders Patients should adhere to rehabilitation exercises; develop a balanced diet with low fat and high fiber.