Itchy toes long blisters (“blisters”) need to be treated according to the cause of the disease: if it is tinea pedis, the main antifungal drug treatment; if it is eczema, you can use boric acid solution, hydrocortisone cream and other drugs to treat. 1. Tinea pedis: especially the fungal infection caused by blister type tinea pedis, will cause the symptoms of toe long blisters itching. First of all, you need to keep the skin clean and hygienic, avoid sweat infiltration, avoid soaking in water, and wear shoes with better breathability. Treatment, if the blisters are not ruptured, you can use clotrimazole cream, terbinafine cream and other antifungal drugs; if the blisters are ruptured and oozing, it is recommended to use boric acid solution and other wet compresses, to be free of oozing, and then the local application of antifungal drugs. 2. Eczema: Inflammatory skin diseases caused by internal and external stimulation of a variety of factors can also cause itchy blisters on the toes. First of all, we need to actively search for the cause, and avoid the cause to aggravate the symptoms. Treatment, if the blisters are not broken can be used glucocorticoid cream, such as hydrocortisone cream, dexamethasone cream; if the blisters rupture oozing, available boric acid solution and other wet compresses, to be free of exudate, and then the local application of glucocorticoid creams; if the itching is serious, you can comply with the doctor’s instructions for oral antihistamine drugs, such as cetirizine, loratadine. Toe long blisters itching may have other reasons, it is recommended that patients first go to the hospital for examination, clear diagnosis and treatment as prescribed by the doctor.