Amenorrhea does not indicate that polycystic ovary syndrome is very serious, amenorrhea is a common symptom of polycystic ovary syndrome, in addition to polycystic ovary syndrome will be abnormal menstruation, hyperandrogenism, insulin resistance-related metabolic abnormalities, infertility and other symptoms. 1. Abnormal menstruation and ovulation: Abnormal menstruation can be characterized by irregular cycles, scanty menstruation, low menstrual flow, or amenorrhea (cessation of menstruation for more than 3 previous menstrual cycles or ≥6 months), and some unpredictable bleeding may also occur. Ovulatory abnormalities are mainly characterized by sporadic ovulation (no ovulation for ≥3 months per year) or anovulation. 2. Hyperandrogenism: Clinical manifestations are often accompanied by signs of hirsutism, acne, alopecia, and masculinization. 3. Metabolic abnormalities associated with insulin resistance: Obesity (mostly abdominal obesity), acanthosis nigricans, impaired glucose regulation/type 2 diabetes mellitus, abnormal lipid metabolism, non-alcoholic fatty liver disease, hypertension, cardiovascular disease risk, and other clinical signs are common. 4. Infertility: Polycystic ovary syndrome can lead to abnormal ovulation, sporadic ovulation or anovulation, which may lead to higher infertility rate. Polycystic ovary syndrome needs to be based on the patient’s medical history and clinical manifestations, combined with diagnostic imaging and a variety of laboratory indicators, if amenorrhea and other clinical symptoms, it is recommended that the patient go to the hospital in a timely manner, under the guidance of the doctor to comply with the instructions of the medication, as well as diet and exercise to assist in the intervention.