Patients with high creatinine generally have renal failure or renal insufficiency, and there are differences in treatment for different causes, as follows: 1, acute renal failure: more common factors are dehydration, or prolonged diarrhea, sweating can cause insufficient blood volume, which leads to high creatinine, this situation will improve the renal function mainly through rehydration and correction of blood volume; 2, urinary tract obstruction: more common are urinary tract stones, urinary tract tumor and secondary tumor compression of the ureter, Urological tumors and secondary tumors compressing the ureter, mainly according to different causes for different treatments, such as stones causing obstruction can be removed through lithotripsy or surgery; if caused by urological tumors, comprehensive treatment may be required for tumors; 3, high creatinine caused by chronic renal failure: high creatinine caused by chronic renal failure has different causes, including chronic nephritis, secondary diabetes, hypertension, multiple Secondary factors such as chronic nephritis, secondary diabetes, hypertension, multiple myeloma, etc., should be treated first, such as diabetes caused by the control of blood sugar, early use of insulin; hypertension caused by the control of blood pressure stable; if it reaches the late stage of renal failure, the main treatment of complications, such as anemia can be corrected by supplementation of erythropoietin and iron, supplementation of calcium to correct hypocalcemia, metabolic acidosis can be corrected by sodium bicarbonate; uremia late through The late stage of uremia should be treated by hemodialysis or peritoneal dialysis, and patients with conditions can be treated by kidney transplantation.