Patients should distinguish whether it is migraine or hemiplegic headache. Generally, right-sided headache is mainly seen in the following diseases: 1. Migraine, patients mainly show vascular pulsation-like headache near the right temple, and there may be precursory symptoms such as photophobia and blurred vision before the headache. It is often triggered by mental tension, exertion and anger, and the pain may be accompanied by nausea and vomiting, etc. The patient’s symptoms may be significantly reduced after rest or oral pain medication, and there are often no special findings on cranial imaging. 2. Trigeminal neuralgia, trigeminal neuralgia is often located on one side, and the nature of the pain is mainly knife-like or itchy. It is triggered when washing the face and brushing the teeth for a relatively short period of time but the degree of intensity, patients can take oral carbamazepine or trigeminal nerve vascular decompression for treatment. 3, frontal sinusitis, frontal sinusitis is also a common cause of headache on one side, patients can also be accompanied by dizziness, nasal congestion, runny nose and other symptoms. The symptoms can be reduced after the temperature rises in winter and spring, and the cause can be further clarified by CT or MRI examination of the sinuses. In addition, it can also be caused by intracranial tumor, intracranial vascular malformation, herpes zoster and other diseases, and patients are advised to consult neurology, neurosurgery or dermatology.