There are many ways to remove the callus of the skin, such as medication, physical therapy and so on. 1. medication: patients can follow the doctor’s instructions to use Vitamin A cream and other drugs to improve the symptoms, but also with the use of salicylic acid ointment, urea ointment to exfoliate, so that they fall off. 2. Physical therapy: for minor skin calluses, you can use warm water to soak it, soak and then use professional tools to grind and scrape the calluses, but the way to operate several times, can not be removed at once, so as not to damage to the skin. In addition, liquid nitrogen cryotherapy can also remove skin calluses, through the ultra-low temperature to freeze the skin calluses, so that it gradually dry, fall off, so as to achieve the purpose of removal. There are many ways to remove skin calluses, it is recommended that patients go to the hospital in a timely manner, follow the doctor’s instructions to use the appropriate medication, not private treatment, so as not to lead to adverse consequences.