Glioblastoma is a relatively high incidence of intracranial tumors, with rapid onset, rapid progression, extremely poor prognosis, and short survival time for patients. First, the symptoms caused by the location of the lesion may cause aphasia, hallucinations, hallucinations, impaired physical activity, choking and coughing if it is located in the functional area; second, the lesion itself may cause high cranial pressure, jet vomiting and severe headache in the advanced stage; third, metastasis of glioblastoma is rare and occurs mainly in the vertebral body. Thirdly, glioblastoma is less likely to metastasize, mainly in the vertebral body, and the probability is relatively low, and the late symptoms are mainly concentrated in the intracranial area.