There is no relationship between the occurrence of gray hair and vitamin B6, so, with gray hair on the head, taking vitamin B6 usually has no effect. Vitamin B6 is a commonly used western medicine in clinical practice, mainly including injections, tablets, ointments, etc. It is a vitamin drug, in which the main ingredient is vitamin B6, which can be used for vitamin B6 deficiency-induced related diseases and prevention. Vitamin B6 can be used against nicotinic acid hydrazine poisoning, but also for radiation sickness, pregnancy, vomiting caused by anticancer drugs, seborrheic dermatitis and so on. Vitamin B6 can also be given for supplementation of progressive weight loss due to inadequate vitamin B6 intake and total parenteral nutrition. Gray hair is a common clinical symptom, mainly including physiological gray hair and pathological gray hair. With age, the body functions gradually decline, the hair follicle melanin synthesis may be reduced leading to gray hair, is a normal phenomenon, generally do not need special treatment. Hereditary progeria, hereditary defects, albinism, vitiligo, tuberculosis, neurological lesions, thyroid disease, excessive anxiety and sadness, vitamin deficiencies and other factors may lead to premature gray hair on the head. In summary, gray hair may be caused by physiological factors and usually does not require treatment. Vitamin B6 is a vitamin drug that can be used to prevent vitamin B6 deficiency or vitamin B6 deficiency, and is generally not used in the treatment of gray hair. If gray hair is suspected to be caused by certain diseases, it is recommended to go to the hospital to find the cause and treat for the primary disease.