H. pylori can cause chronic gastritis in patients, so as long as the patient’s H. pylori is treated, the symptoms of chronic gastritis will also be relieved. The treatment of H. pylori infection in the clinic is mainly triple therapy and quadruple therapy, of which quadruple therapy is used more often in the clinic. Patients can treat and relieve their symptoms with four drugs at the same time under the guidance of a physician. These four drugs contain a proton pump inhibitor and a gastric mucosal protector, plus two antibiotics, which together make up the drugs needed for quadruple therapy. The main drugs include, but are not limited to, amoxicillin, clarithromycin, colloidal bismuth, esomeprazole, and other drugs. These four drugs can be used for symptomatic treatment under the guidance of a physician, with a typical treatment cycle of about 14 days, which can be extended appropriately in some patients.