Ulcerative colitis may have no definitive medication to eradicate it and usually requires a combination of treatments to improve symptoms. Common oral medications include mesalazine and methylprednisolone. The cause of ulcerative colitis is unclear and is related to genetics, immunity, environment, and infection. Oral drugs can be categorized into aminosalicylic acid preparations, hormones, immunosuppressants, probiotics, mucosal repair agents and so on. 1. Aminosalicylic acid preparations: such as salazosulfapyridine and mesalazine. 2. Hormones, such as dexamethasone and methylprednisolone. 3. Immunosuppressants: e.g. cyclophosphamide, methotrexate, etc. 4. Probiotics: e.g. Bifidobacterium bifidum quadruple live bacterial tablets, Bacillus licheniformis live bacterial capsules, etc. 5. Mucosal protective agents: such as compound glutamine capsule, montelukast, etc.. Oral drugs such as the effect is not good also need to consider enemas, anal plugging drugs, surgical treatment, etc., specific should be combined with the condition of comprehensive consideration. For the treatment of ulcerative colitis, it is recommended to actively consult a doctor to formulate a systematic treatment plan, and the medication should be carried out under the guidance of the doctor.